
The study analysed the outcomes of 4,068 cases of resuscitation attempts performed by laypeople on adults who had collapsed from cardiac arrest. The observational study was based in the Kanto area in Japan, and is said to be is the first large-scale account comparing the survival rates of out-of-hospital cardiac arrest patients who were treated either with or without mouth-to-mouth ventilations by bystanders at the scene.
According to the study, which was led by Gordon A Ewy, director of the University of Arizona's Sarver Heart Center, mouth-to-mouth breathing takes too much time away from chest compressions, which have to be continuous to improve the chance of survival.
"We have found that the survival rate is higher even when the blood has less oxygen content, but is moved through the body by continuous chest compressions, than when the blood contains a lot of oxygen but is not circulated well because chest compressions are interrupted for mouth-to-mouth ventilations," Ewy said.

The study was published on March 17 in The Lancet. More information is available from the University of Arizona's press release.
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